A Crack in Creation

The most important advance of our era. One of the pioneers of the field describes the exciting hunt for the key breakthrough and what it portends for our future

Walter Isaacson

An urgent plea from the celebrated biologist whose discovery enabled us to rewrite the code of life. The future is in our hands as never before, and this book explains the stakes like no other

George Lucas

Urgent, riveting and endlessly fascinating, this book is destined to become an instant classic. Read it if you want to understand our biological future

Siddhartha Mukherjee

An exhilarating and frightening roadmap to our future by one of the most pioneering women in science

Arianna Huffington

Jennifer Doudna is the true pioneer who built the bridge between the basic science of CRISPR and its diverse applications. Now is the time to read about the revolution that could change our world

George Church

A scientific thriller and a gripping read by a brilliant scientist

Venki Ramakrishnan

One of the most monumental discoveries in biology

New York Times

Too important … What may happen thanks to Doudna’s [discovery] is dizzying … for her, this is the future of medicine. If she’s right, then Crispr is about to make our present healthcare concerns look surprisingly trivial

Bryan Appleyard, Sunday Times

Probably the greatest biological breakthrough since that of Francis Crick, James Watson and Rosalind Franklin… We owe Doudna several times over – for her discovery, for her zeal to take it from the lab into the clinic, for her involvement in the ethical issues raised, for her public engagement work, and now for this book

Peter Forbes, Guardian

One of the architects of this miraculous biological technique … explains the science clearly and excitingly as a kind of globalist detective story

Telegraph

In this wonderful book … Doudna’s and Sternberg’s simple but compelling exploration of this hugely important subject offers and excellent overview of this startling and unprecedented discovery

Literary Review

A detailed account of the story so far. It may well end up being compared with the book that inspired a 12-year-old Doudna in the first place: James Watson’s The Double Helix … Packed with amazing female scientists, it is thrilling, generous and no less personal … We need scientifically informed conversations about what we should do next with these powers, and Doudna’s book is a good place to begin

Adam Rutherford, New Scientist

A welcome new contribution to the [gene editing] debate… She should be congratulated for being one of the very few scientists involved in a breakthrough to write a timely, popular personal account… Doudna’s style, more contemplative than Watson or Venter, is just as effective at describing the increasingly frantic pace of life in the lab, as researchers realise that epoch-making discoveries are in the offing. She tells the scientific back-story particularly well… The arguments are rehearsed with admirable clarity

Clive Cookson, Financial Times